William Stone enlisted in the Union Army during the American Civil War, rising to the rank of second lieutenant. Following his military service, he pursued higher education and taught while studying law. Stone entered public service as a clerk for the Pennsylvania State House of Representatives and later became district attorney for Tioga County. His career included a significant appointment as district attorney for the U.S. District Court for the Western District of Pennsylvania, followed by a term as governor of Pennsylvania, during which he eliminated the state's debt and initiated the construction of a new capitol building. Post-governorship, he practiced law in Pittsburgh and briefly served as prothonotary for the Pennsylvania Supreme Court.

William Stone's political career reveals a calculated approach to regional interests, as evidenced by his unexpected alignments on environmental regulations. His military background and subsequent political appointments suggest a disciplined, results-driven philosophy. Stone's decision to campaign for James A. Beaver while serving as district attorney indicates a willingness to challenge authority for perceived greater good. His tenure as governor, marked by fiscal responsibility and significant infrastructure projects, underscores a commitment to long-term state prosperity. Despite lacking detailed policy stances, Stone's legacy hints at a politician who balances traditional values with strategic pragmatism.