Oscar De Los Santos holds a strong academic background, having earned a Bachelor of Arts in political science from the University of Southern California, followed by a master's in public policy from St Antony's College, Oxford. He furthered his education with a master's degree in Christian social ethics and is currently pursuing a Juris Doctor at Yale Law School. De Los Santos has experience in both the public and private sectors, having taught at a high school and interned for notable institutions. He currently leads public policy for the Association of Arizona Food Banks.

Oscar De Los Santos consistently champions progressive policies while advocating for marginalized communities, presenting a unique blend of social justice and economic equity. His legislative efforts to eliminate medical debt and protect voting rights highlight a commitment to human rights. De Los Santos's opposition to the ESA voucher system and the Right to Work law reveals a calculated approach to preserving public resources and labor standards. His stance on climate justice, particularly targeting mega-polluters in working-class areas, shows a strategic focus on environmental equity. De Los Santos's ideological agility and unexpected policy combinations make his approach both intriguing and multifaceted.