Lita Indzel Cohen was born in 1940 and graduated from Lower Merion High School in 1958. She completed her undergraduate studies at the University of Pennsylvania in 1962 and earned a law degree from the University of Pennsylvania Law School in 1965. Cohen made history as the first woman elected to the Lower Merion Township Planning Commission and served as a Lower Merion Township Commissioner for eight years. She spent nearly two decades in public service, including a term in the Pennsylvania House of Representatives, before transitioning to other professional endeavors.

Lita Indzel Cohen's political journey is marked by a blend of pioneering roles and strategic electoral decisions, suggesting a calculated approach to her career. Her early achievements, such as being the first woman elected to the Lower Merion Township Planning Commission, indicate a commitment to breaking barriers. Despite running as a Republican, her legislative record shows an unexpected convergence with opposing factions on environmental regulations, revealing a highly localized approach to policymaking. Cohen's decision to step away from the House of Representatives after a single term, followed by a run for the Senate, underscores an ideologically agile stance, possibly driven by a nuanced understanding of regional political dynamics.