George Watkins began his career learning shipfitting in Newport News, Virginia, and later moved to Chester, Pennsylvania, where he organized the Chester Stevedoring Company. He founded the Blue Line Transfer Company in 1932, serving as its president and board chairman. Watkins transitioned into public service, holding positions such as Sheriff of Delaware County, Pennsylvania, State Senator, and County Commissioner. He spent several terms in the U.S. Congress, where he focused on issues related to transportation and commerce, particularly advocating for the trucking industry.

George Watkins's political identity is shaped by an unwavering commitment to local interests, particularly within Delaware County, Pennsylvania. His strategic opposition to reapportionment and redistricting highlights a highly localized approach, driven by a belief that Delaware County's population warranted continued representation. Watkins's advocacy for the trucking industry reveals an ideological alignment with regional economic concerns, suggesting a policy framework that prioritizes local commerce over broader national trends. His rhetorical style, marked by direct public opposition to state-level redistricting plans, indicates a willingness to challenge established processes for the sake of local governance.