George Burnham began his career as a clerk before transitioning into retail and real estate. He relocated multiple times, gaining experience in various industries, including ranching. Burnham's professional journey included significant roles in organizing major expositions and serving on multiple commissions, indicating a broad range of expertise. His involvement in banking and public service, particularly in education and community development, underscores a commitment to economic and civic advancement. Burnham's experience in international trade and diplomacy further highlights his diverse professional background.

George Burnham's career reveals a multifaceted approach to public service, blending economic development with a commitment to community and international engagement. His involvement in real estate and banking suggests a pragmatic focus on economic growth, yet his participation in organizing major expositions and commissions points to a broader vision for public affairs. Burnham's role in the Honorary Commercial Commission to China indicates an early interest in global trade, a stance that juxtaposes his local business endeavors. His dedication to educational institutions through the Library Commissions showcases a nuanced understanding of the interplay between economic prosperity and community enrichment.