Frank Merriam began his career in education, serving as a school principal and superintendent in Iowa and Nebraska. He transitioned into journalism, owning and publishing newspapers in Oklahoma and California. His political career started in Iowa, where he served in the state legislature and as state auditor. He later moved to California, where he held various positions in the state legislature, including Speaker of the California State Assembly. Merriam's leadership culminated in his tenure as governor of California, following the death of Governor Rolph. Post-governorship, he remained active in civic organizations and briefly ran for U.S. Senate.

Frank Merriam's political career is marked by a blend of educational leadership and legislative pragmatism, with a notable shift from Iowa to California. His tenure in various educational roles before entering politics suggests an early commitment to public service and community development. His legislative career, particularly his election as Speaker of the California State Assembly, indicates a knack for navigating complex political landscapes. Merriam's unexpected convergence with opposing factions on certain issues hints at a strategic, perhaps regionally tailored approach to governance. His later life involvement with the California Society of the Sons of the American Revolution adds a layer of historical consciousness to his political persona.