Enoch Louis Lowe graduated first in his class and was admitted to the bar. He spent several years in public service, including a term in the Maryland House of Delegates and a tenure as Governor of Maryland. Lowe's career included a significant period in high-finance, followed by a move to the public sector. He was a U.S. Presidential elector and a member of the Democratic National Convention. Lowe's professional expertise and leadership capabilities were recognized by his peers, including James McSherry, Chief Judge of the Court of Appeals of Maryland.

Enoch Louis Lowe's political identity is marked by a distinctive blend of fiscal conservatism and regional loyalty. His advocacy for reducing state taxes while simultaneously supporting the Confederacy reveals a complex interplay between economic policy and regional allegiance. Lowe's legislative achievements, such as overseeing the completion of the Baltimore and Ohio Railroad, demonstrate a calculated approach to infrastructure that aligns with his broader strategic interests. This juxtaposition of economic measures and regional loyalty invites deeper inquiry into how Lowe balances these seemingly disparate priorities.