Edwin Winans pursued a multifaceted career marked by significant transitions and leadership roles. He began his professional journey in the milling industry before studying law at the University of Michigan. Winans ventured into mining during the California Gold Rush, where he gained experience in banking and mining operations. Upon returning to Michigan, he engaged in local politics, holding various positions including state representative, township supervisor, and probate judge. Winans's career culminated in his election to the U.S. House of Representatives and his tenure as Governor of Michigan, during which he implemented election reforms.

Edwin Winans's political career is marked by a blend of regional pragmatism and ideological adaptability, as evidenced by his advocacy for election reform and implementation of the secret Australian ballot. His involvement in the California Gold Rush and subsequent return to Michigan highlight a life of economic mobility and local engagement. Winans's career, spanning various local and state offices, suggests a strategic focus on regional interests, particularly in election integrity and local governance.