Charles C. Comstock spent several decades in the lumber and manufacturing sectors, establishing a furniture factory and later the Grand Rapids Chair Company. He served as Mayor of Grand Rapids and pursued various political campaigns, including runs for Governor of Michigan and a seat in the United States House of Representatives. Comstock's career highlights his commitment to economic development and public service in Michigan.

Charles C. Comstock's political career reveals a deeply localized approach, consistently advocating for the economic interests of Grand Rapids, Michigan, particularly in lumber and manufacturing. His unique ideological positioning is evident in his shifting party affiliations, from Democrat to Greenbacker, showcasing an adaptable yet focused strategy on regional economic development. Comstock's legislative actions, like supporting machinery for local manufacturing and establishing the Grand Rapids Chair Company, highlight an unexpected alignment with industrial growth while maintaining a local business focus.